Self-tuning of neural circuits through short-term synaptic plasticity
D. Sussillo, T. Toyoizumi, and W. Maass
Circuits of neurons in the cortex have a remarkable capability to maintain
functional and dynamic stability in spite of changes in the level of external
inputs, synaptic plasticity and changes in the circuit structure that occur
during development and adult learning. The source of this characteristic
stability of cortical circuits has remained a mystery, especially since even
stronglysimplified models of such circuits do not exhibit similar stability
properties. One simplification that is usually made in such models is that
the empirically found nonlinear and diverse inherent short term dynamics
(paired-pulse facilitation and depression) of biological synapses is replaced
by static and uniform linear synapse models. We show in this article that
this is a mistake, since the complex and diverse nonlinear dynamics of
biological synapses supports the implementation of powerful control
principles that endow circuits of spiking neurons with almost in-vivo like
Reference: D. Sussillo, T. Toyoizumi, and W. Maass.
Self-tuning of neural circuits through short-term synaptic plasticity.
Journal of Neurophysiology, 97:4079-4095, 2007.