Methods for Estimating the Computational Power and Generalization Capability of Neural Microcircuits

W. Maass, R. Legenstein, and N. Bertschinger

Abstract:

What makes a neural microcircuit computationally powerful? Or more precisely, which measurable quantities could explain why one microcircuit $C$ is better suited for a particular family of computational tasks than another microcircuit $C'$? We propose in this article quantitative measures for evaluating the computational power and generalization capability of a neural microcircuit, and apply them to generic neural microcircuit models drawn from different distributions. We validate the proposed measures by comparing their prediction with direct evaluations of the computational performance of these microcircuit models. This procedure is applied first to microcircuit models that differ with regard to the spatial range of synaptic connections and with regard to the scale of synaptic efficacies in the circuit, and then to microcircuit models that differ with regard to the level of background input currents and the level of noise on the membrane potential of neurons. In this case the proposed method allows us to quantify differences in the computational power and generalization capability of circuits in different dynamic regimes (UP- and DOWN-states) that have been demonstrated through intracellular recordings in vivo.



Reference: W. Maass, R. Legenstein, and N. Bertschinger. Methods for estimating the computational power and generalization capability of neural microcircuits. In L. K. Saul, Y. Weiss, and L. Bottou, editors, Advances in Neural Information Processing Systems, volume 17, pages 865-872. MIT Press, 2005.